New observational study compares the effectiveness of the Pfizer-BioNTech and Moderna COVID vaccine third doses

A new research article published in Nature Microbiology using electronic health records of US veterans has found that, in comparison with the Pfizer-BioNTech vaccine, a third dose of the Moderna vaccine was more effective in preventing infection, symptomatic COVID-19, hospitalization, and death. In the absence of direct head-to-head studies looking at the third dose of the Pfizer-BioNTech and Moderna mRNA-based COVID vaccines, the team, led by researchers from Harvard T.H. Chan School of Public Health, sought to understand their comparative effectiveness. Using population data from the United States Department of Veterans Affairs healthcare databases, the largest integrated healthcare system in...