NICE’s real-world evidence framework in action: an interview with Pall Jonsson and Stephen Duffield, NICE, UK

Establishing trust in real-world data (RWD) and real-world evidence (RWE) is key to supporting its broader use in decision-making in both regulatory and health technology assessment (HTA) settings. Several organizations have released guidance and frameworks providing advice on the design and reporting of RWE to support policy decisions, including the National Institute for Health and Care Excellence (NICE) who published the ‘NICE real-world evidence framework’ in June 2022. One year on, following the publication of their Editorial ‘The real-world impact of National Institute for Health and Care Excellence's real-world evidence framework’ in the Journal of Comparative Effectiveness Research, we speak...