Hot off the press: our picks of real-world evidence articles published in April 2024

Our monthly feature curating select articles across the spectrum of real-world evidence (RWE) research published in April 2024. Use of quantitative bias analysis to evaluate single-arm trials with real-world data external controls The integration of external controls derived from real-world data (RWD) into single-arm trials is increasingly being used to augment traditional trial designs. However, it's crucial to ensure the quality, integrity, and relevance of the RWD used as external controls and to employ robust methodologies to address potential biases and confounding factors. Endorsed by the International Society for Pharmacoepidemiology (ISPE), through illustrative examples this article explores how quantitative bias...