PREVENT CLOT study shows aspirin as effective as low-molecular-weight heparin for thromboprophylaxis in people hospitalized with bone fractures

Findings of the patient-centered outcomes PREVENT CLOT trial likely to change standard of care in orthopaedic trauma clot prevention The results of a landmark clinical trial, PREVENTion of CLots in Orthopaedic Trauma (PREVENT CLOT), showing inexpensive over-the-counter oral aspirin is as effective as injected blood thinner for preventing life-threatening blood clots in orthopaedic trauma patients have been published in the New England Journal of Medicine. The pragmatic, multicenter, randomized, noninferiority trial is the largest ever conducted to assess thromboprophylaxis in orthopaedic trauma patients and was co-led by the Department of Orthopaedics at the University of Maryland School of Medicine (UMSOM) and...