Can appendectomies cause Parkinson's disease? Abstract highlights from day 3 of ISPOR Europe 2019

As part of our continuous coverage of the ISPOR Europe 2019 (2–6 November; Copenhagen, Denmark) meeting, we bring you our abstract highlights from the third and final day of the conference: Parkinson's disease, multiple sclerosis and more!

Go to the profile of The Evidence Base
Nov 06, 2019
0
0

Abstract highlights:

Can appendectomies cause Parkinson's disease?
Predicting multiple sclerosis relapses with a claims-based algorithm
How to develop and evaluate outcomes-based agreements for medical devices


Can appendectomies cause Parkinson's disease?

Following recent suggestions that appendectomy surgeries can increase individuals’ risks of developing Parkinson’s disease (PD), researchers from The University of Tokyo and Milliman Inc. (both Tokyo, Japan) have conducted a US claims database review of 13,951 individuals with PD who underwent appendectomies and compared their outcomes to 13,927 matched control persons with PD, who underwent no, or other, surgeries.

The results of the study demonstrate no statistically significant association between patients’ undergoing appendectomy surgery and having increased, or reduced, likelihood of developing PD.

Read more

Back to top of page


Predicting multiple sclerosis relapses with a claims-based algorithm

Relapse frequency is a well-regarded parameter from which to assess the real-world efficacies of disease-modifying therapies for multiple sclerosis. In this study, led by researchers from Bordeaux University (France), a novel algorithm for detecting relapse frequencies based on claims data was applied to the French nationwide claims database (SNIIRAM/SNDS).

The claims-based algorithm was found to successfully identify patients with and without relapses with at least 95% accuracy. The results of the study therefore demonstrate the potential of applying such technology in future observational, claims-based studies.

Read more

Back to top of page


How to develop and evaluate outcomes-based agreements for medical devices

Outcomes-based agreements are being increasingly implemented to address uncertainty surrounding the value delivered by medical devices. As a result, it has become ever more important to evaluate the associated outcomes-risks pf these agreements. In a novel study, an international team of Johnson & Johnson Medical researchers from the Netherlands, France and the USA have applied basic statistical principles to the risk evaluation of outcomes-based agreements. This study specifically focused on outcomes-based agreements aimed at reducing surgical-site infections.

The study highlights the importance of collaboration in developing and selecting appropriate and achievable outcomes-based agreements that are beneficial to all stakeholders, with risk transparency.

Read more

Back to top of page


Stop by booth #C2-026 to meet The Evidence Base® and Journal of Comparative Effectiveness Research teams, and receive a free gift!


Go to the profile of The Evidence Base

The Evidence Base

Community, Future Medicine

The Evidence Base is a community site covering the latest news, opinion and insight into the collection and application of real-world data to real-world problems.
55 Contributions
4 Followers
0 Following

No comments yet.