Real-world evidence FAQs
Got a question about real-world evidence, health economics and outcomes research (HEOR) or decision making? Read our frequently asked questions (FAQs) below!
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What is real world evidence?
Real-world evidence (RWE) is evidence obtained from real world data (RWD), which are observational data obtained outside the context of randomized controlled trials and generated during routine clinical practice. RWE is generated by analyzing data which is stored in electronic health records (EHR), medical claims or billing activities databases, registries, patient-generated data, mobile devices, etc.
Where does real-world data come from?
Real world data (RWD) is derived from a number of sources that are associated with outcomes in a heterogeneous patient population in real-world settings, such as patient surveys, clinical trials, and observational cohort studies.
What are electronic health records?
Systematized collection of patient and population electronically-stored health information in a digital format. They are often used as a source of real-world data.
What is comparative effectiveness research?
The conduct and/or synthesis of research comparing different benefits and harms of alternative interventions and strategies to prevent, diagnose, treat, and monitor health conditions in routine clinical practice (i.e. the real world setting). Comparative effectiveness research includes both primary data collection and secondary analyses (such as systematic literature reviews, meta-analyses and economic evaluations).